Human Wingless Type MMTV Integration Site Family, Member 11 (WNT11) ELISA Kit

Quantitative measurement of WNT11 in human research samples is enabled by this ELISA kit from Assay Genie, supplied as a 96-assay research-use-only microplate format. WNT11 (Wingless-type MMTV integration site family, member 11) is a secreted cysteine-rich glycoprotein that activates non-canonical Wnt signaling cascades, with particular involvement in β-catenin-independent pathways governing cell polarity, directed cell migration, and tissue morphogenesis. The protein has well-documented roles in cardiac development, where it influences outflow tract formation and cardiomyocyte specification, as well as in neural crest cell behavior, kidney organogenesis, and skeletal patterning.

The kit accommodates tissue homogenates, cell lysates, and cell culture supernatants, supporting in vitro studies in developmental biology, oncology, and regenerative medicine research. WNT11 expression has been investigated in contexts such as hepatocellular carcinoma, breast cancer progression, and cardiac repair, where its modulation of RhoA, JNK, and PKC signaling pathways is of mechanistic interest. Reagent components include pre-coated plate wells, recombinant standards, biotinylated detection antibody, streptavidin-HRP conjugate, wash buffer, substrate solution, and stop reagent, supplied in single-use vials sufficient for quantitative analysis of WNT11 protein in experimental samples. For research use only; not intended for diagnostic or clinical applications.