Human Wingless Type MMTV Integration Site Family, Member 10A (WNT10A) ELISA Kit

Researchers examining WNT-pathway signaling in developmental and dermatological contexts use this Assay Genie ELISA Kit to quantify human WNT10A protein for research use only. WNT10A is a secreted signaling glycoprotein that activates the canonical beta-catenin pathway and has been linked through genetic studies to ectodermal differentiation, including tooth morphogenesis, hair follicle development, and nail formation. The 96 assays format kit supports protein-level investigations in dental anomalies, hair biology, and regenerative medicine workflows.

Tissue homogenates and cell lysates serve as the primary input matrices, supporting applications such as pathway signaling research, gene expression cross-validation alongside PCR, and protein-level analysis of WNT10A in transfected or stimulated cell lines. Reagents are configured for processing multiple sample replicates alongside a standard curve, supplied as a complete set sufficient for a single microplate workflow.

Background context: WNT10A dysregulation has been reported in amelogenesis imperfecta and hypodontia cases, and the protein remains a target of interest for stem-cell differentiation and regenerative dentistry research. Published studies have used anti-WNT10A antibodies to confirm expression in murine dental epithelium, while human sample work often examines gingival tissue biopsies or osteoblast cell culture models.