Human Willin ELISA Kit (HUFI05651)

The Willin protein (gene symbol FRMD6, also called FERM domain-containing protein 6) is a ~72 kDa cytoskeletal adaptor that participates in the Hippo growth-control pathway, where it helps restrain YAP/TAZ-driven transcription in response to cell density and mechanical cues. This quantitative immunoassay from Assay Genie is configured as a 96 Assays plate-based kit, intended for research use only in studies of human samples, including investigations into meningioma biology, Schwann cell myelination, and Merlin/NF2-related signaling.

Researchers use this assay to profile Willin expression across cell lines and primary tissues where the Hippo tumor-suppressor network is being characterized, including glioblastoma models, peripheral nerve sheath tumors, and studies of contact inhibition. Each kit provides reagents for 96 Assays, shipped in a vial-based format suitable for laboratory research workflows. Willin detection complements parallel readouts of YAP, TAZ, and Merlin, since the FERM domain of FRMD6 mediates upstream inputs that regulate proliferative versus differentiation outcomes in epithelial and glial contexts.