Human WDR4 ELISA Kit (HUFI05659)

Quantitative measurement of WDR4 (WD Repeat Domain 4) protein levels in human samples is supported by this ELISA Kit from Assay Genie. WDR4 functions as a non-catalytic subunit of the m7G46 tRNA methyltransferase complex, a key player in tRNA maturation and ribosome biogenesis. Loss-of-function mutations in WDR4 have been implicated in Galloway-Mowat syndrome, a rare condition presenting with microcephaly, intellectual disability, and nephrotic syndrome, making this kit relevant for translational studies of neurodevelopmental and renal disease.

Investigators studying tRNA modification machinery, ribosome biogenesis disorders, and developmental biology apply this kit in cell culture, biochemistry, and molecular pathology workflows. Sample handling best practices include aliquoting immediately after collection and storing at -80 °C to preserve analyte integrity through repeated freeze-thaw cycles. Intended for in vitro research use only in academic and pharmaceutical laboratories, the reagents are supplied in vials and are compatible with standard microplate readers. Capture antibodies, detection antibodies, standards, and buffers are included for the complete assay workflow.