Human VPS45 ELISA Kit (HUFI05707)

The Assay Genie Human VPS45 ELISA Kit enables quantitative measurement of the Sec1/Munc18-family trafficking regulator vacuolar protein sorting-associated protein 45 in human biofluid samples. VPS45 controls SNARE-mediated membrane fusion during endosomal and lysosomal biogenesis, and loss-of-function mutations underlie VPS45-associated leukoencephalopathy, a rare neurodegenerative disorder. Investigators studying inherited leukodystrophies, neurodegenerative disease biomarkers, and membrane trafficking pathways can apply this microplate-based immunoassay to patient samples and cell culture-derived material in vitro. Reconstituted reagents should be stored frozen at -20°C, protected from light, and used within the stated shelf life to maintain capture antibody performance.