Human VPS26A ELISA Kit (HUFI05698)

VPS26A (Vacuolar Protein Sorting 26 Homolog A) is the ~38 kDa subunit of the retromer complex, a trimeric scaffold that mediates retrograde transport of cargo receptors from endosomes back to the trans-Golgi network. By pairing with VPS29 and VPS35, VPS26A stabilises the complex and supports the proper sorting of mannose 6-phosphate receptors, sortilin-related receptors, and Wntless, linking it to Wnt signaling, amyloid precursor protein trafficking, and to neurodegenerative pathways implicated in Parkinson's disease.

The Assay Genie Human VPS26A immunoassay is configured for quantitative measurement in human blood fractions and cell lysate samples, with a recommended 100 uL sample volume per well. Researchers aliquot reconstituted standards, freeze them for storage, and limit freeze-thaw cycles to preserve signal. Each pack contains a pre-coated microplate, biotinylated detection antibody, HRP-streptavidin conjugate, wash buffer, substrate, and stop solution, supporting research use only in cell biology, neuroscience, and receptor trafficking studies.