Human Von Willebrand Factor Cleaving Protease (vWFCP) ELISA Kit

Investigators studying hemostasis, von Willebrand factor biology, and thrombotic microangiopathies can use this Assay Genie kit to quantify Von Willebrand Factor Cleaving Protease (vWFCP) in human specimens. vWFCP, also known as ADAMTS13, is the metalloprotease responsible for cleaving ultra-large von Willebrand factor multimers in circulation, and reduced activity of this enzyme is the central molecular feature of Thrombotic Thrombocytopenic Purpura (TTP), supporting research into congenital TTP (Upshaw-Schulman syndrome), acquired idiopathic TTP, and secondary forms linked to autoimmune and infectious triggers.

The immunoassay is configured as a 96-assay microplate ELISA with a colorimetric endpoint read on a standard plate reader, and the kit includes reagents, standards, and consumables sufficient for the indicated run size. Specimen guidance covers standard venipuncture blood draws processed to yield human serum or citrated/EDTA plasma fractions, with aliquots stored frozen to limit freeze-thaw cycles prior to testing. Intended for research use only, the kit supports investigator-initiated studies of ADAMTS13 antigen levels, complementing functional assays used to evaluate VWF-cleaving activity in clinical research cohorts.