Human Vitamin K-dependent protein S (PROS1) ELISA Kit

Designed by Assay Genie for the quantitative measurement of human Vitamin K-dependent protein S (PROS1), this Sandwich ELISA kit is intended for cardiovascular research and uses a colorimetric detection method.

The assay accepts serum, plasma, tissue homogenates, cell culture supernates and other biological fluids. It is specific to natural and recombinant human Vitamin K-dependent protein S, with a detection range of 6.25-400 ng/mL and a sensitivity of 1.56 ng/mL. PROS1 is described as an anticoagulant plasma protein that acts as a cofactor to activated protein C in the degradation of coagulation factors Va and VIIIa, helping to prevent coagulation and stimulating fibrinolysis.

Precision figures reported include an Intra CV of 5.6% and an Inter CV of 10.2%. Linearity across serum (N=5) is 109-118% at 1:2, 101-113% at 1:4, 82-91% at 1:8 and 82-90% at 1:16; EDTA plasma (N=5) shows 87-97%, 99-108%, 102-111% and 112-122%; Heparin plasma (N=5) shows 81-94%, 97-107%, 102-113% and 109-119%. Recovery averages 106% (range 100-112%) in serum and 108% (range 102-114%) in plasma. Subcellular location is reported as secreted. For research use only.