Human Vasopressin V1a receptor (AVPR1A) ELISA Kit

Designed for the accurate detection of Vasopressin V1a receptor (AVPR1A) levels in human serum, plasma, tissue homogenates, cell culture supernates, and other biological fluids, this colorimetric Sandwich ELISA Kit from Assay Genie offers specificity for both natural and recombinant human Vasopressin V1a receptor. The AVPR1A receptor plays a critical role in regulating vasoconstriction and blood pressure, making it a key target in the study of cardiovascular diseases, hypertension, and other related conditions. Its activity is mediated by G proteins that activate a phosphatidyl-inositol-calcium second messenger system, and the receptor has been involved in social behaviors, including affiliation and attachment.

Reported performance characteristics include a detection range of 0.156-10ng/mL, a sensitivity of 0.067ng/mL, an intra-assay CV of 5.1%, and an inter-assay CV of 9.6%. Linearity has been evaluated in serum (93-125% across 1:2 to 1:16 dilutions), EDTA plasma (99-120%), and heparin plasma (83-117%). Recovery averages 103% for serum (range 97-109%) and 105% for plasma (range 99-111%). The kit is intended for research use only, supporting applications in neurosciences and broader biomedical research aimed at understanding the AVPR1A pathway.