Human VANGL2 ELISA Kit (HUFI05732)

Van Gogh-like protein 2 (VANGL2) is a transmembrane component of the non-canonical Wnt/planar cell polarity signaling pathway, and Assay Genie's Human VANGL2 ELISA Kit delivers quantitative measurement of this protein in research specimens. The kit contains reagents for 96 Assays and is supplied for research use only, supporting laboratories investigating cell polarity, neural development, and tumor biology where VANGL2 expression is a relevant readout.

VANGL2 — also referenced in the literature as Strabismus (STB1), KITENIN, and LTAP — contributes to planar cell polarity across epithelial sheets, neural tube closure during embryogenesis, and oriented cell migration. Aberrant VANGL2 levels have been examined in studies of neural tube defects, colorectal and gastric cancer progression, and epithelial morphogenesis, making quantitative protein detection valuable for hypothesis-driven research.

The assay is configured for measurement in human serum or plasma specimens and produces a colorimetric signal that can be read on a standard microplate reader. Reagents are packaged in individual vials for reconstitution and use, and the kit supports workflows involving patient-derived samples, cultured cell line extracts, or xenograft tissue lysates, with stability suitable for aliquoting upon receipt and short-term refrigerated storage between experimental runs.