Human V-Erb B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (ErbB3) ELISA Kit

The ErbB3 receptor tyrosine kinase, also called HER3, partners with other ErbB family members—most notably HER2—to drive proliferative and survival signaling through the PI3K/AKT and MAPK cascades. Aberrant ErbB3 expression and ligand-driven activation by heregulin/NRG1 are implicated in several solid tumors, including breast, gastric, and ovarian cancers, and have become a focal point for studies of resistance to HER2-targeted therapeutics. ErbB3 is a ~148 kDa transmembrane glycoprotein belonging to the EGFR family.

This quantitative immunoassay from Assay Genie is configured to measure ErbB3 across a panel of clinically relevant specimen types—including serum samples, plasma samples, tissue homogenates, and related sample matrices—supporting oncology, signaling, and biomarker research workflows. The kit ships as a 96-assay configuration with the reagents needed to generate a standard curve and quantify unknown samples in parallel. The procedure uses an absorbance readout on a standard microplate reader, compatible with instruments commonly used for routine ELISA work in most laboratories.

Intended for research use only, the kit supports investigations into receptor overexpression, ligand response, and pathway activity across patient-derived materials and cell-line models.