Human Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA) ELISA Kit

The Assay Genie human UACA ELISA kit enables quantitative measurement of Uveal Autoantigen with Coiled-coil domains and Ankyrin repeats in human tissue homogenates using an absorbance-based method on a standard microplate reader.

UACA is a multi-domain regulatory protein originally identified as an autoantigen in ocular autoimmune disease and subsequently characterized as a stress-responsive regulator of apoptosis and NF-κB signaling. Researchers studying Vogt-Koyanagi-Harada syndrome, sympathetic ophthalmia, and related autoimmune uveitis conditions frequently use this target in in vitro studies of patient-derived samples. Beyond autoimmunity, UACA has attracted interest in cancer biology due to its role in modulating cell death pathways under endoplasmic reticulum stress.

This 96-assay format kit is intended for research use only and supports laboratory workflows investigating autoantibody profiling, apoptotic signaling, and ocular inflammation. The colorimetric readout allows standard absorbance instrumentation to be used without specialized equipment.