Human USP46 ELISA Kit (HUFI05738)

The Assay Genie Human USP46 ELISA Kit enables quantitative measurement of Ubiquitin-Specific Protease 46, a deubiquitinating enzyme studied in neurological disorders, circadian biology, and oncology research. USP46 modulates protein turnover by cleaving ubiquitin chains from substrate polypeptides, with reported roles in regulating GABA-A receptor stability at neuronal synapses and contributing to proteostasis pathways implicated in tumor cell proliferation.

The microplate strip wells accommodate blood-derived specimens, with researchers typically loading 100 µL of diluted sample per well during the assay run. The capture antibody is human-specific, minimizing cross-reactivity with homologous proteases from other species. Reconstituted standards and detection antibody should be stored frozen at -20°C for prolonged shelf life, and partial-plate workflows are supported through removable 8-well strip units.

For research use only. Not intended for clinical diagnostic procedures.