Human USP19 ELISA Kit (HUFI05763)

USP19 (Ubiquitin Specific Peptidase 19) is a large deubiquitinating enzyme of approximately 150 kDa that regulates protein homeostasis through the ubiquitin-proteasome system. It modulates ER-associated degradation, innate immunity signaling, and skeletal muscle maintenance, making circulating USP19 a candidate biomarker in research on cancer cachexia, viral replication, and chronic inflammation.

The Assay Genie kit ships with a pre-coated microplate, biotinylated detection antibody, streptavidin-HRP conjugate, TMB substrate, and recombinant USP19 standards for curve generation. Researchers typically pair ELISA readouts with Western blot confirmation or immunohistochemistry on matched tissue samples to localize expression patterns. Reconstituted standards should be aliquoted and frozen to limit freeze-thaw damage, and the working detection antibody is generally prepared fresh before each run. The kit is for research use only and is not validated for clinical diagnostics.