Human UNC45B ELISA Kit (HUFI08327)

UNC-45 myosin chaperone B (UNC45B), a member of the UCS domain protein family that cooperates with Hsp90 to direct proper folding, stabilization, and assembly of myosin heavy chains into functional sarcomeres, can be quantitatively measured using this ELISA Kit from Assay Genie.

Beyond its canonical role in striated muscle maturation and contractile function, UNC45B contributes to non-muscle myosin-dependent processes including cytokinesis, cell migration, and intracellular trafficking. Loss-of-function mutations in UNC45B have been linked to congenital neuromuscular disorders and skeletal myopathies, while altered expression has been reported in cardiomyopathies and certain tumor contexts. Investigators in muscle biology, cardiovascular research, motor protein biochemistry, and chaperone mechanism studies will find this kit useful for assessing endogenous UNC45B levels in clinical and experimental specimens.

Supplied in a 96 Assays configuration, the assay uses a colorimetric absorbance readout on a microplate for straightforward spectrophotometric quantification. Reagents are validated specifically for samples of human origin, and each kit provides sufficient reagents for ninety-six individual determinations, supporting medium-throughput experimental designs in basic and translational research settings.