Human UIMC1 ELISA Kit (HUFI05800)

UIMC1, also known as RAP80, acts as a scaffold in the BRCA1-A complex, recognizing K63-linked ubiquitin chains at DNA double-strand breaks and recruiting BRCA1 to sites of chromatin damage. Assay Genie provides this quantitative immunoassay, validated specifically for detection of human UIMC1 in clinical specimens and cell-line lysates, to support research in breast cancer biology, homologous recombination repair, and ubiquitin-dependent signaling. The microplate-based workflow allows quantification of the endogenous protein in human samples using a sample volume of 100 µL per well, and the kit includes pre-coated wells, detection reagents, standards, and substrate for in vitro research use only. Components arrive refrigerated and should be stored according to the manual to preserve antibody activity across repeated freeze-thaw cycles. Investigators focused on DNA damage response biomarkers, BRCA1 pathway mutations, or genotoxic stress signaling will find this assay a practical addition to translational oncology studies.