Human UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1) ELISA Kit

UGT1A1 is a hepatic phase II enzyme that catalyzes the transfer of glucuronic acid from UDP-glucuronic acid to bilirubin, phenolic metabolites, and certain drugs, including the chemotherapeutic irinotecan. Polymorphisms in the UGT1A1 gene are clinically associated with Gilbert syndrome and Crigler-Najjar types I and II, so quantitative measurement of UGT1A1 protein supports hepatic-function studies, bilirubin metabolism research, and pharmacogenomics workflows.

This Assay Genie microplate assay accepts cell lysates, tissue homogenates, and similar research specimens, making it useful for liver biopsy material, cultured hepatocyte preparations, and recombinant enzyme expression samples. Reagents are intended for research use only and should be refrigerated upon arrival to preserve antibody binding activity across the standard shelf life.