Human UDP Glucose Ceramide Glucosyltransferase (UGCG) ELISA Kit

This quantitative immunoassay from Assay Genie enables measurement of UDP-glucose:ceramide glucosyltransferase (UGCG) in human samples. UGCG catalyzes the first glycosylation step in glucosylceramide biosynthesis, producing the precursor for higher-order glycosphingolipids that shape membrane composition and cell signaling. Researchers use UGCG quantification to investigate glycosphingolipid metabolism, drug resistance phenotypes in cancer cell models, and lipid-mediated signaling pathways.

The kit is supplied in a 96-assay microplate configuration using a colorimetric method. The assay is validated for use with tissue homogenates and cell lysates prepared from human origin material. Each plate provides sufficient reagents to run a full standard curve alongside experimental samples, supporting reliable quantitation across a working range appropriate for cell and tissue extracts.

Applications include screening of pharmacological modulators of glucosylceramide synthesis, characterization of UGCG expression in tumor cell lines and primary tissues, and investigation of the enzyme's role in cell signaling pathways. The kit is intended for research use only and is not cleared for diagnostic procedures.