Human ucMGP (undercarboxylated matrix gla protein) ELISA Kit (HUFI08032)

Vascular calcification and vitamin K metabolism research requires precise detection of circulating protein biomarkers. Undercarboxylated matrix Gla protein (ucMGP) has emerged as a key indicator in this field, reflecting suboptimal vitamin K status and serving as an early signal of soft tissue mineralization. The Human ucMGP ELISA Kit from Assay Genie delivers quantitative measurement of this inactive MGP fraction in human specimens, supporting translational studies of cardiovascular calcification, dialysis-related mineral disorders, and nutritional vitamin K research.

This microplate-format immunoassay uses a two-antibody capture configuration with chromogenic signal development for sensitive readout. Reagents are supplied for one full microplate run, accommodating standard curve generation alongside experimental replicates. The included protocol covers specimen handling, dilution series, and quantitative data analysis workflows.

Primary research applications include:

• Investigation of vascular and soft tissue calcification pathways
• Vitamin K status assessment and supplementation response studies
• Cardiovascular risk biomarker discovery
• Chronic kidney disease and hemodialysis patient research
• Bone mineralization and mineral metabolism studies

Validated specifically for human matrix components. Intended for research use only.