Human Ubiquitin Protein Ligase E3A (UBE3A) ELISA Kit

UBE3A is an E3 ubiquitin ligase encoded within the chromosome 15q11-q13 region, where maternal allele disruption causes Angelman syndrome and imprinting abnormalities connect this gene to Prader-Willi syndrome. The Assay Genie UBE3A ELISA enables quantitative measurement of this ligase for neurodevelopmental disorder research, cancer pathway investigations, and synaptic plasticity studies. The assay supports investigation of ubiquitin-proteasome pathway dynamics, neuronal protein turnover, and imprinting regulation across experimental conditions. Researchers exploring autism spectrum disorder biomarkers, HPV E6-mediated p53 degradation mechanisms, or neurodegenerative disease models can profile ligase expression using this ELISA format. Store reagents refrigerated and protect from light to maintain stability across repeated freeze-thaw cycles.