Human Ubiquitin Protein Ligase E3 Component N-Recognin 4 (UBR4) ELISA Kit

This ELISA Kit from Assay Genie enables quantitative measurement of human Ubiquitin Protein Ligase E3 Component N-Recognin 4 (UBR4) in research samples. UBR4 is a large (~600 kDa) E3 ligase functioning as an N-recognin in the N-end rule pathway of the ubiquitin-proteasome system; it binds destabilizing N-terminal residues on substrate proteins and directs them toward proteasomal degradation. Also referenced in the literature as p600 or ZUBR1, UBR4 has been investigated in the contexts of neural development, protein homeostasis, and tumor biology, making this reagent of interest to researchers exploring N-terminal protein quality control. The assay is calibrated for use with tissue homogenates and supplied in a 96 assays kit format, with components packaged in individual vials for in vitro research use only. A colorimetric protocol supports straightforward signal readout on standard microplate readers. Users should consult the included product insert for storage conditions, shelf life, and the recommended sample volume per well. This product is intended for research applications and has not been validated for diagnostic or clinical use.