Human UBE2G1 ELISA Kit (HUFI08333)

UBE2G1 (Ubiquitin-Conjugating Enzyme E2G 1) belongs to the E2 ubiquitin-conjugating enzyme family and participates in the ubiquitin-proteasome system that regulates protein turnover and quality control in eukaryotic cells. The Assay Genie kit enables quantitative measurement of UBE2G1 protein in human specimens, supporting studies in cell biology, neurodegeneration, and ER-associated degradation (ERAD) research.

Each kit arrives as a complete microplate package containing pre-coated wells, biotinylated detection antibody, recombinant protein standards, and all buffers required for the run. Researchers apply this ELISA in vitro to monitor UBE2G1 expression changes following proteasome inhibition, oxidative stress exposure, or treatment with experimental compounds. All reagents ship refrigerated; unopened kits remain stable at 4 °C for the duration indicated on the label, and reconstituted standards should be aliquoted and frozen to limit freeze-thaw cycles.

UBE2G1 collaborates with specific E3 ligases to ubiquitinate substrate proteins destined for proteasomal destruction, and altered UBE2G1 expression has been linked to Parkinson’s disease pathology and several cancer types. The assay provides a quantitative readout to advance research into these mechanisms.