Human Tyrosine Kinase 2 (Tyk2) ELISA Kit

Built around a quantitative immunoassay workflow, this Assay Genie kit measures human Tyrosine Kinase 2 (Tyk2) levels for research laboratories investigating JAK-STAT signaling, interferon-driven inflammation, and autoimmune disease mechanisms.

Tyk2 is a Janus-family non-receptor tyrosine kinase encoded on chromosome 19p13.2. It couples type I interferon, IL-12, IL-23, and IL-10 receptor activation to downstream STAT phosphorylation, and biallelic TYK2 deficiency in humans produces a primary immunodeficiency characterized by impaired antiviral responses. Studies of cytokine response profiling, kinase inhibitor screening, and immune cell signaling frequently rely on Tyk2 expression data, which this kit helps generate from tissue homogenates and cell lysates.

For reagent integrity, store the unopened kit refrigerated and protect from light until first use; reconstituted standards and detection antibodies should be handled per the supplied protocol. The kit format supports standard laboratory workflows, and the product is intended for research use only, not for diagnostic procedures.