Human TYRO3  (Tyrosine-protein kinase receptor TYRO3) ELISA Kit (HUFI08058)

This Assay Genie quantitative immunoassay measures human TYRO3, a member of the TAM receptor tyrosine kinase family that regulates immune cell function, phagocytic clearance of apoptotic cells, platelet aggregation, and nervous system development. Intended for research use only, the kit supports investigations into cancer biology, neurobiology, and inflammatory signaling, where altered TAM receptor activity has been reported.

TYRO3 (Tyrosine-protein kinase receptor TYRO3) is a transmembrane receptor with intrinsic kinase activity that binds the vitamin K–dependent ligands GAS6 and Protein S, activating downstream PI3K/AKT and MAPK pathways. Aberrant TYRO3 expression has been documented in melanoma, glioblastoma, and acute myeloid leukemia research, making it a target of interest in tumor biology and immunology studies. The 96 Assays format accommodates multi-sample experimental designs and replicate measurements, and each assay plate provides quantitative readouts suited to comparing TYRO3 protein levels across experimental conditions.

Applications include cell culture supernatant analysis, biomarker discovery, and pathway-focused investigations of TAM receptor signaling in human disease models. Researchers working on AXL/MER/TYRO3 crosstalk, vitamin K–dependent signaling, or apoptosis regulation can use this assay to monitor TYRO3 changes under pharmacological or genetic perturbation.