Human Tumor necrosis factor receptor superfamily member 12A (TNFRSF12A) ELISA Kit

From Assay Genie, this Sandwich-format ELISA kit is designed for the quantitative detection of human Tumor necrosis factor receptor superfamily member 12A (TNFRSF12A), also known by synonyms including Tweak-receptor, TweakR, CD266, FN14, and FGF-inducible 14. The assay is intended for research use only and accepts human serum, plasma, tissue homogenates, cell culture supernates and other biological fluids as sample types.

According to the manufacturer, the kit delivers a detection range of 0.156-10 ng/mL with a sensitivity of 0.067 ng/mL. Reported precision values are an intra-assay CV of 4.9% and an inter-assay CV of 8.4%. Linearity in serum spans 89-115% across dilution ratios of 1:2 to 1:16, with EDTA plasma between 100-118% and heparin plasma between 95-115%. Average recovery is 103% (range 97-109%) for serum and 105% (range 99-111%) for plasma.

TNFRSF12A functions as a receptor for TNFSF12/TWEAK and is associated with TRAF1 and TRAF2, with reported roles in inflammatory responses, angiogenesis, and cell death. The UniProt accession is Q9NP84, and the manufacturer highlights cancer as the primary research area, with applications relevant to autoimmune and inflammatory disease studies.