Human TTK/PYT PharmaGenie ELISA Kit (SBRS1208)

From Assay Genie, this TTK/PYT ELISA quantifies a dual-specificity protein kinase (also called Mps1) that safeguards accurate chromosome segregation through the spindle assembly checkpoint. Because TTK activity is elevated in proliferating tumor cells, this human-specific capture antibody assay is used to profile kinase expression across breast, lung, pancreatic, and colorectal carcinoma models compared with matched normal tissue controls.

The immunoassay ships with prepacked antibody-coated wells and a complete reagent set sufficient for up to 96 individual determinations, accommodating dose-response studies of small-molecule Mps1 inhibitors, siRNA knockdowns, and chemotherapeutic agents in cell-based research workflows.

For reproducible data, store unopened components refrigerated at the temperature recommended on the vial label, equilibrate reagents to room temperature before use, and limit freeze-thaw cycles of the reconstituted standards. Investigators studying mitotic checkpoint fidelity, aneuploidy, or oncology drug response frequently pair TTK protein quantification with Western blot analysis of phospho-TTK signaling and downstream checkpoint effectors.