Human Tryptophan Hydroxylase 2 (TPH2) ELISA Kit

This quantitative immunoassay from Assay Genie targets Tryptophan Hydroxylase 2 (TPH2), the brain-enriched isoform of the rate-limiting enzyme in serotonin biosynthesis. The kit is configured for 96 assays and is validated for use with human-derived serum samples, plasma specimens, and tissue homogenates.

TPH2 catalyzes the conversion of tryptophan to 5-hydroxytryptophan within serotonergic neurons of the dorsal raphe and other midbrain nuclei, making it a widely studied biomarker in neurochemistry. Researchers investigating mood disorders, anxiety, aggression, sleep regulation, and the neurobiology of psychiatric disease routinely measure TPH2 protein levels to understand changes in enzyme expression across different experimental conditions, brain regions, and subject cohorts.

The assay uses a colorimetric readout compatible with standard laboratory microplate readers. Each kit includes the essential reagents needed to run the complete plate protocol, supporting reproducible quantification of TPH2 concentration in research-use samples. Protocols are intended for in vitro research applications only.