Human Tripeptidyl Peptidase I (TPP1) ELISA Kit

Quantitative measurement of Tripeptidyl Peptidase I (TPP1) protein in human research samples is supported by this immunoassay kit from Assay Genie, supplied as a 96-assay format for studies in lysosomal biology and neurodegenerative disease research. TPP1 is a lysosomal serine protease that cleaves tripeptides from the N-terminus of polypeptides, and loss-of-function mutations in the TPP1 gene are the molecular cause of CLN2 disease (neuronal ceroid lipofuscinosis type 2, also known as late infantile Batten disease), making accurate protein quantification important in disease modeling and therapeutic response studies.

Built around a microplate protocol with a colorimetric readout, the kit enables straightforward absorbance measurement on standard plate readers. Validated sample types include tissue homogenates and cell lysates, supporting work across cultured cell lines, animal model tissues, and human biopsy material. Sufficient reagents are included to generate full standard curves and to evaluate unknown samples alongside appropriate experimental controls.

The kit is intended for laboratory professionals studying lysosomal function, enzyme replacement therapy outcomes, and biomarker discovery in Batten disease and related neurodegenerative contexts. Protocols are documented for users with standard ELISA experience, and the included components support both single-point quantification and serial dilution workflows in a research use only setting.