Human Tripartite motif-containing protein 72 (TRIM72) ELISA Kit

From Assay Genie, this sandwich ELISA kit is designed for the precise quantification of human Tripartite motif-containing protein 72 (TRIM72), also known by the synonyms Mitsugumin-53, Mg53, and MG53. The assay is reactive with human samples and accepts serum, plasma, tissue homogenates, cell culture supernates, and other biological fluids. It demonstrates specificity for natural and recombinant human TRIM72.

The kit offers a detection range of 0.156-10ng/mL with a sensitivity of 0.081ng/mL. Intra-assay precision is reported at an Intra CV of 5.9% and inter-assay precision at an Inter CV of 8.4%. Linearity has been evaluated in serum, EDTA plasma, and heparin plasma across dilution ratios of 1:2, 1:4, 1:8, and 1:16 (N=5 per matrix). Recovery averages 95% for serum (range 89-101%) and 97% for plasma (range 91-103%).

TRIM72 is a muscle-specific protein that plays a central role in cell membrane repair by nucleating the assembly of repair machinery at injury sites and specifically binds phosphatidylserine. The protein is implicated in muscle regeneration and repair as well as other cellular processes such as autophagy and inflammation, with dysregulation linked to muscular dystrophy, cancer, and metabolic disorders, highlighting its relevance as a potential biomarker. The UniProt accession is Q6ZMU5 and the research area is Cell Biology. For research use only.