Human Triosephosphate isomerase (TPI1) ELISA Kit

From Assay Genie, this Sandwich ELISA Kit is designed for the quantitative measurement of human Triosephosphate isomerase (TPI1). It employs a colorimetric detection method and is reactive with human samples, with specificity for natural and recombinant human TPI. Reported synonyms for the target include Methylglyoxal synthase, Triose-phosphate isomerase, TIM, and TPI.

According to the manufacturer's specifications, the kit has a detection range of 0.78-50 ng/mL and a sensitivity of 0.34 ng/mL. Reported precision values are an intra-assay CV of 5.1% and an inter-assay CV of 8.6%. Validated sample types include serum, plasma, tissue homogenates, cell culture supernates and other biological fluids.

Triosephosphate isomerase is a homodimeric, cytoplasmic enzyme central to glycolysis and energy metabolism. Defects in TPI1 are associated with triosephosphate isomerase deficiency, an autosomal recessive disorder recognised as the most severe clinical disorder of glycolysis. The kit is intended for research use only.