Human Transmembrane protein 126A (TMEM126A) ELISA Kit

Manufactured by Assay Genie, this Sandwich ELISA provides quantitative measurement of human Transmembrane protein 126A (TMEM126A) in serum, plasma, tissue homogenates, cell culture supernates, and other biological fluids. The colorimetric assay is for research use only, is reactive with human samples, and shows specificity for natural and recombinant human TMEM126A.

Performance characteristics include a detection range of 0.156–10 ng/mL, a sensitivity of 0.098 ng/mL, an intra-assay CV of 3.5%, and an inter-assay CV of 7.4%. Linearity was demonstrated across serial dilutions in serum, EDTA plasma, and heparin plasma. Recovery averaged 85% (range 80–91%) in serum and 87% (range 81–93%) in plasma.

TMEM126A is a multi-pass transmembrane protein located at the mitochondrion inner membrane, with a molecular weight of 22 kDa, that plays a role in cellular function, particularly in mitochondrial health and energy metabolism. The gene maps to chromosomal location 11q14.1 (UniProt Q9H061, NCBI Gene ID 84233). Defects in TMEM126A are the cause of optic atrophy type 7 (OPA7), an autosomal recessive juvenile-onset condition. The kit is associated with the immunology research area.