Human Transmembrane protease serine 4 (TMPRSS4) ELISA Kit

A sandwich ELISA kit from Assay Genie designed for the quantitative measurement of human Transmembrane protease serine 4 (TMPRSS4). The assay is intended for research use only and detects natural and recombinant human TMPRSS4 in serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.

Reported performance characteristics include a detection range of 0.78-50 ng/mL and a sensitivity of 0.34 ng/mL. Intra-assay CV is 4.5% and inter-assay CV is 8.2%. Linearity in serum (N=5) ranges from 104-119% across dilutions of 1:2 to 1:16; EDTA plasma (N=5) ranges from 80-113% and heparin plasma (N=5) ranges from 91-120%. Recovery averages 92% for serum (range 86-98%) and 94% for plasma (range 88-100%).

TMPRSS4 is described as a transmembrane protease involved in cellular processes including cell signaling and migration, with dysregulation linked to cancer and inflammation. It is annotated as a probable protease capable of activating ENaC. The protein is a single-pass type II membrane protein with a molecular weight of 55 kDa (UniProt Q9NRS4, NCBI Gene ID: 56649), and the research area is cell biology.