Human Transcriptional repressor CTCF (CTCF) ELISA Kit

Assay Genie provides an ELISA platform for the quantitative measurement of human Transcriptional repressor CTCF, a sequence-specific DNA-binding protein also known as CCCTC-binding factor. CTCF functions as a critical transcriptional repressor and chromatin insulator, and its dysregulation has been implicated in cancer, autoimmune disorders, and developmental abnormalities, underscoring its value as a research target.

The kit is validated for use with serum, plasma, tissue homogenates, cell culture supernates and other biological fluids. It delivers a detection range of 0.312-20ng/mL and a sensitivity of 0.172ng/mL. The product is intended for research use only within the Epigenetics research area.

CTCF is a widely expressed transcriptional regulator containing 11 C2H2-type zinc fingers, acting as both a transcriptional activator and repressor depending on chromatin context. The protein localizes to the nucleus, nucleoplasm, chromosomes and centromeres, and is associated with UniProt accession P49711.