Human Transcription factor 7-like 2 (TCF7L2) ELISA Kit

The Assay Genie Sandwich ELISA Kit enables the colorimetric detection and quantification of human Transcription factor 7-like 2 (TCF7L2) protein in biological samples. TCF7L2 is a transcription factor that participates in the Wnt signaling pathway, modulating MYC expression by binding to its promoter in a sequence-specific manner. Dysregulation of TCF7L2 has been implicated in several diseases, such as diabetes, cancer, and inflammatory disorders, making it a valuable target for biomarker studies and therapeutic development.

The kit has a detection range of 78-5000pg/mL and a sensitivity of 54pg/mL, with an intra-assay CV of 4.8% and inter-assay CV of 7.5%. It is specific to natural and recombinant human Transcription factor 7-like 2 and is intended for use with serum, plasma, tissue homogenates, cell culture supernates, and other biological fluids. Synonyms include HMG box transcription factor 4, T-cell-specific transcription factor 4, T-cell factor 4, and TCF4. The associated Uniprot ID is Q9NQB0, and the research area is Epigenetics. The protein localizes to the nucleus and PML bodies. For research use only.