Human TRAIL R4 PharmaGenie ELISA Kit (SBRS1184)

The TRAIL R4 (TNFRSF10D) immunoassay from Assay Genie enables quantitative measurement of the decoy receptor DcR2 in human cell culture supernatant, plasma or serum samples. TRAIL R4, also known as DcR2 or TRAIL receptor without an intracellular death domain, binds TNF-related apoptosis-inducing ligand (TRAIL) but fails to transduce the apoptotic signal, instead modulating ligand availability at the cell surface. The kit is configured for 96 assays per plate and uses a colorimetric readout compatible with standard microplate readers.

Researchers studying cancer cell resistance to TRAIL-induced apoptosis, decoy receptor regulation in oncology, immune checkpoint biology, or inflammatory signalling pathways rely on this kit to quantify DcR2 levels. Applications include monitoring TRAIL pathway components in tumour cell lines, profiling receptor expression in immune disorders, and characterising drug response in apoptosis research. Each kit provides reagents sufficient for a single plate run and is intended for research use only, supporting workflows ranging from biomarker discovery through to preclinical compound screening where decoy-receptor activity influences treatment outcome.