Human Topoisomerase II (TOP2) ELISA Kit

Quantitative measurement of human DNA topoisomerase II (TOP2), a nuclear enzyme essential for relieving DNA topological strain during replication, transcription, and chromosome segregation, underpins oncology research into tumor proliferation markers and resistance to topoisomerase-targeting chemotherapeutics such as etoposide and doxorubicin. The Assay Genie ELISA kit is configured for 96 assays and accepts tissue homogenates, cell lysates, and other sample matrices, supporting laboratories that profile TOP2 expression across patient-derived material and cultured cell line panels. Reagents arrive in ready-to-use vials; store the kit refrigerated at 4°C and protect from light to preserve activity through the stated shelf life. Intended for research use only, the assay is not validated for diagnostic decision-making. Investigators studying topoisomerase II alpha as a prognostic indicator in breast, ovarian, or colorectal carcinoma, or screening compound libraries for novel TOP2 inhibitors, will find this immunoassay useful for high-throughput quantification alongside confirmatory western blot experiments.