Human Topoisomerase I (TOP1) ELISA Kit

Measuring TOP1 protein expression in human samples forms the basis of this research-use ELISA Kit offered by Assay Genie. Topoisomerase I is a nuclear enzyme that relieves torsional strain in supercoiled DNA during replication and transcription, and altered expression of TOP1 is linked to tumor proliferation, chemotherapeutic response, and DNA damage response studies.

Each kit is configured for 96 assays, intended for research use only, and supports applications such as biomarker quantification, inhibitor screening, and comparative expression profiling between normal and diseased tissue samples. Sample preparation follows standard homogenization and lysis protocols, and results are interpreted against a standard curve generated from recombinant TOP1 reference material.

Built for oncology, molecular pharmacology, and DNA metabolism research, this kit serves labs investigating TOP1 as a target of camptothecin-class inhibitors and as a marker of cellular proliferation in tumor versus normal tissue comparisons.