Human Toll Like Receptor 9 (TLR9) ELISA Kit

TLR9 (Toll-like receptor 9) is an endosomal pattern recognition receptor central to innate immunity, where it recognizes unmethylated CpG DNA motifs common in bacterial and viral genomes. Receptor engagement activates MyD88-dependent signaling, driving NF-κB and IRF7 translocation and the production of type I interferons and pro-inflammatory cytokines.

This quantitative ELISA from Assay Genie is configured for measurement of TLR9 in human tissue homogenates, cell lysates, and cell culture supernatants. The kit is supplied in a microplate format providing 96 assays per plate, along with all reagents required for a standard quantitative immunoassay workflow. It is intended for research use only.

Typical applications include studies of innate immune activation in infectious disease models, characterization of TLR9 expression in autoimmune and chronic inflammatory disorders, evaluation of candidate vaccine adjuvants, and screening of small-molecule immunomodulators acting on the TLR9 signaling axis.