Human TNFSF9 (Tumor necrosis factor ligand superfamily member 9) ELISA Kit (HUFI08026)

TNFSF9, the type II transmembrane co-stimulatory ligand also known as 4-1BBL, engages the TNFRSF9 receptor on activated T cells and drives proliferation, IL-2 and IFN-γ secretion, and survival of CD8+ effector populations. Because this signaling axis shapes antitumor immunity and chronic inflammation, soluble TNFSF9 is a frequently monitored biomarker in immuno-oncology, vaccine adjuvant development, and autoimmune disease research.

The Assay Genie Human TNFSF9 ELISA Kit provides quantitative measurement of the ligand across 96 Assays per kit, with all required components supplied: pre-coated microplate, biotinylated detection antibody, standard diluent, streptavidin-HRP conjugate, substrate solution, and a detailed protocol. Researchers apply the kit to human cell culture supernatants, primary immune cell cultures, and translational sample cohorts to track ligand shedding after T-cell activation or checkpoint blockade treatment.

By pairing a robust colorimetric readout with reproducible standard curves, the kit supports pharmacodynamic evaluation of costimulatory agonists, characterization of CAR-T constructs bearing 4-1BB signaling domains, and longitudinal monitoring of patient-derived specimens across preclinical and translational workflows.