Human TNF receptor-associated factor 6 (TRAF6) ELISA Kit

Designed for the precise and sensitive quantification of human TNF receptor-associated factor 6 (TRAF6), this Sandwich ELISA kit from Assay Genie provides high accuracy and reproducibility for a range of research applications. TRAF6 is a key regulator of inflammatory and immune responses, with dysregulation linked to autoimmune disorders, inflammatory conditions and cancer, so quantitative monitoring supports studies of disease mechanisms and potential therapeutic targets.

The assay detects TRAF6 in serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids, with specificity for natural and recombinant human TRAF6. Performance characteristics include a detection range of 0.156-10 ng/mL and a sensitivity of 0.078 ng/mL. Intra-assay CV is 6.5% and inter-assay CV is 10.2%. Linearity has been validated in serum, EDTA plasma and heparin plasma at dilutions of 1:2, 1:4, 1:8 and 1:16. Recovery in serum averages 95% (range 89-101%) and in plasma averages 97% (range 91-103%).

Alternative names covered include E3 ubiquitin-protein ligase TRAF6, Interleukin-1 signal transducer, RING finger protein 85, RING-type E3 ubiquitin transferase TRAF6 and RNF85, with the UniProt reference Q9Y4K3. The kit is intended for research use only in immunology research.