Human TMEM199 ELISA Kit (HUFI06061)

Transmembrane protein 199 (TMEM199) localizes to the ER-Golgi intermediate compartment, where it supports COPI-coated vesicle trafficking and contributes to assembly of the vacuolar H+-ATPase. Loss-of-function variants in the corresponding gene have been linked to a congenital disorder of glycosylation (CDG type II), making quantitative readouts of the protein valuable for biomarker discovery and pathway analysis in affected cohorts. This in vitro research-use-only immunoassay kit from Assay Genie is configured as a colorimetric microplate method for measuring TMEM199 in human samples, supplied as a complete kit containing the coated plate, detection reagents, buffers, and protocol documentation needed to process a single 96 Assays batch.

Typical laboratory applications include screening patient-derived specimens, characterizing V-ATPase assembly factor dysfunction, and basic investigations of ER-to-Golgi membrane transport. Each pack supports standardized bench workflows and is intended for research use only, not for diagnostic procedures. Refer to the enclosed package insert for storage temperature, recommended sample handling, and step-by-step procedural guidance.