Human TMCC2 ELISA Kit (HUFI06086)

Quantitative measurement of Transmembrane and Coiled-Coil Domains 2 (TMCC2) protein in human specimens is supported by this colorimetric ELISA offering from Assay Genie, configured as a complete 96 Assays package. The assay targets a neuronal and endoplasmic-reticulum-associated protein that has drawn research attention in Alzheimer's disease studies, where TMCC2's interaction with amyloid precursor protein (APP) was reported and continues to inform work on amyloidogenic processing and amyloid-beta biology.

Each kit includes a pre-coated microplate and reagents sufficient for ninety-six determinations, supporting medium-throughput screening of experimental samples. Researchers investigating endosomal trafficking, ER membrane dynamics, and neurodegenerative biomarkers can use the kit to quantify TMCC2 levels and monitor expression changes in disease models or treatment cohorts. The colorimetric readout is captured on a standard microplate reader, generating absorbance data that can be compared across plates with the included reference standards.

Beyond Alzheimer's research, TMCC2 is examined for its contributions to endolysosomal trafficking and ER-associated membrane remodeling, processes relevant to a broad spectrum of neurodegenerative mechanisms. Application areas include mechanistic cell biology, biomarker validation, and translational neuroscience, with each assay plate produced under lot-controlled manufacturing to support reproducibility across experimental runs.