Human Tissue Inhibitors Of Metalloproteinase 3 (TIMP3) ELISA Kit

TIMP3 is the only tissue inhibitor of metalloproteinases that binds directly to the extracellular matrix, where it restrains MMP, ADAM, and ADAMTS activity. Because of this anchoring behavior, TIMP3 measurements in clinical specimens serve as a meaningful readout of matrix turnover in fibrotic disorders, tumor microenvironment studies, age-related macular degeneration research, and cardiovascular remodeling investigations. The Assay Genie Human TIMP3 ELISA Kit is configured as a microplate immunoassay with reagents supplied for 96 individual determinations and is reactive with human specimens including serum samples, plasma preparations, and tissue homogenate fractions. Researchers investigating Sorsby fundus dystrophy, hepatic stellate cell activation, glioblastoma invasion, or vascular injury responses commonly incorporate TIMP3 quantification into their biomarker panels. Components should be refrigerated for storage and equilibrated to room temperature before each assay run; protect substrate solutions from prolonged light exposure to maintain detection performance. The kit supports standard ELISA workflows and integrates readily with cell culture supernatant analysis, tissue lysate profiling, and other research use only applications in matrix biology and inflammation studies.