Human Tissue factor pathway inhibitor 2 (TFPI2) ELISA Kit

A high-quality Sandwich ELISA Kit from Assay Genie for the detection of human Tissue factor pathway inhibitor 2 (TFPI2), also referred to as placental protein 5, PP5, or TFPI-2. The assay is configured for human reactivity and accepts serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.

Reported performance specifications include a sensitivity of 0.79ng/mL and a detection range of 1.56-100ng/mL, with an intra-assay CV of 6.2% and inter-assay CV of 11.5%. The kit has been evaluated for linearity and recovery across serum, EDTA plasma and heparin plasma matrices, and specifically recognises natural and recombinant human TFPI2.

TFPI2 is a secreted serine-type endopeptidase inhibitor implicated in the regulation of plasmin-mediated matrix remodeling. According to its curated functional annotation, it inhibits trypsin, plasmin, factor VIIa/tissue factor and weakly factor Xa, but has no effect on thrombin. The protein has a reported molecular weight of 25,796 Da, is a member of the Kunitz-type serine proteinase inhibitor family and has been identified as a tumour suppressor gene in several cancers. For research use only.