Human TIMP-1 PharmaGenie ELISA Kit (SBRS1155)

Extracellular matrix turnover is regulated in part by Tissue Inhibitor of Metalloproteinases 1 (TIMP-1), a 28 kDa glycoprotein that controls matrix metalloproteinase (MMP) activity. The Assay Genie Human TIMP-1 PharmaGenie ELISA Kit is an immunoassay that measures this biomarker in translational and preclinical research contexts where TIMP-1 is implicated in wound healing, tumor invasion, fibrotic remodeling, and chronic inflammatory responses.

The assay accommodates multiple human sample types, including plasma or serum specimens, cell culture supernatant, cell lysate, and tissue lysate preparations, supporting workflows across cell-based experiments, animal model validation, and clinical sample profiling. Detection is selective for the human TIMP-1 analyte, consistent with the kit's validated human reactivity profile.

Each microplate-format kit supplies reagents for multiple experimental runs. Reagents are shipped refrigerated and should be stored refrigerated at the temperature indicated on the package insert to preserve activity through the stated shelf life; intended for in vitro research use only.

Applications include oncology studies linking elevated circulating TIMP-1 to disease progression, hepatic and pulmonary fibrosis research, cardiovascular remodeling investigations, and analyses of MMP/TIMP balance in chronic inflammatory disorders. The chromogenic plate-based format is compatible with standard microplate readers and can be paired with MMP quantification to derive net proteolytic activity in tissue samples.