Human TIM-3 PharmaGenie ELISA Kit (SBRS1153)

The TIM-3 (T-cell immunoglobulin and mucin domain-3) protein, also called HAVCR2, is a key immune checkpoint receptor that has emerged as a critical target in cancer immunotherapy research. This Assay Genie Human TIM-3 PharmaGenie ELISA Kit provides researchers with a quantitative tool to measure soluble TIM-3 levels in human specimens, supporting investigations into T-cell exhaustion, tumor immune evasion, and chronic inflammatory conditions.

The kit is configured for 96 assays and uses a colorimetric readout compatible with standard microplate readers. It is validated for cell culture supernatant, plasma, and serum samples, supporting both in vitro experimental work and translational studies involving patient-derived specimens. Researchers studying immune checkpoint pathways, monoclonal antibody therapeutics, and combination immunotherapy regimens use TIM-3 quantification to assess target engagement and treatment response.

The assay supports flow cytometry-adjacent workflows by providing soluble biomarker data that complements cellular phenotyping of exhausted lymphocyte subsets. Each kit includes the necessary pre-coated plate, standards, and detection reagents to complete a full microplate run, with components stored refrigerated between uses. This ELISA is intended for research use only and is not approved for diagnostic applications.