Human Thyroid Peroxidase PharmaGenie ELISA Kit (SBRS1178)

TPO (Thyroid Peroxidase) is the key enzyme in thyroid hormone biosynthesis, catalyzing iodide oxidation and tyrosine iodination on thyroglobulin. Assay Genie supplies this kit primarily for autoimmune thyroiditis research, where anti-TPO antibody titers serve as established biomarkers for Hashimoto's thyroiditis and Graves' disease investigations. Researchers apply it to clinical studies of subclinical hypothyroidism, postpartum thyroid dysfunction, and maternal-fetal thyroid health assessment. The procedure uses a 100 ul sample volume per well with standards prepared across a serial dilution; reconstituted reagents should be stored frozen at -20 degrees C to maintain activity through repeated freeze-thaw cycles. Pre-coated microplate strips enable flexible workflow scaling. The monoclonal capture antibody is human-specific, showing no significant cross-reactivity with lactoperoxidase or myeloperoxidase from related mammalian species.