Human Thioredoxin-interacting protein (TXNIP) ELISA Kit

An ELISA-based assay kit from Assay Genie is designed for the accurate quantification of human Thioredoxin-interacting protein (TXNIP) levels in serum, plasma, and cell culture supernatants. It uses a sandwich ELISA format with colorimetric detection and offers high sensitivity and specificity for a variety of research applications.

TXNIP is a key protein involved in cellular redox homeostasis and the regulation of inflammation and apoptosis. Dysregulation of TXNIP has been linked to various conditions such as diabetes, cardiovascular diseases, and cancer, making it a valuable target for disease research and the development of targeted therapies.

The assay has a detection range of 0.156-10 ng/mL and a sensitivity of 0.039 ng/mL. Intra-assay CV is reported at 5.6% and inter-assay CV at 8.8%. The kit is reactive with human samples and is specific for natural and recombinant human Thioredoxin-interacting protein. Accepted sample types include serum, plasma, tissue homogenates, cell culture supernates, and other biological fluids. Also referred to as Thioredoxin-binding protein 2, Vitamin D3 up-regulated protein 1, and VDUP1 (UniProt Q9H3M7), TXNIP is localised to the cytoplasm. The kit is for research use only, with applications in cancer research.