Human Thimet Oligopeptidase 1 (THOP1) ELISA Kit

A quantitative immunoassay from Assay Genie targets human Thimet Oligopeptidase 1 (THOP1), a zinc-dependent metalloendopeptidase involved in cytosolic peptide trimming, MHC class I antigen presentation, and amyloid-beta processing. The kit is formatted as a 96-assay pack with reagents pre-configured for in vitro research workflows and calibrated for use with tissue homogenates as the primary sample matrix. THOP1 has attracted attention in neurodegenerative disease research, particularly for studies of Alzheimer's-related pathways where this metallopeptidase activity is implicated in amyloid-beta peptide degradation. Each kit contains the components needed for 96 individual determinations on a standard microplate format, supporting both small-cohort studies and screening of experimental tissue samples. The protocol outlines recommended sample preparation, dilution series for the standard curve, and step-by-step assay procedure guidance to help investigators obtain reproducible readings across runs. Assay Genie manufactures this ELISA Kit to support academic, pharmaceutical, and translational research programs focused on protease biology, immune peptide processing, and protein homeostasis in human tissue.