Human TGF-beta RII PharmaGenie ELISA Kit (SBRS1143)

TGF-beta receptor type II sits at the entry point of the canonical Smad signaling cascade, and quantitative measurement of this transmembrane serine/threonine kinase supports fibrosis, oncology, and immunology research programs. The Assay Genie Human TGF-beta RII PharmaGenie ELISA Kit delivers that capability as a colorimetric immunoassay, accepting human cell culture supernatants, plasma, and serum as input, with reagents supplied for 96 determinations across a microplate.

The kit is positioned within the Assay Genie PharmaGenie line for pharmaceutical and biopharma workflows, supporting preclinical target validation, receptor occupancy studies, and compound screening campaigns where reproducible quantification of TGF-beta pathway components is essential. Capture antibody, detection antibody, recombinant standards, and substrate are included so researchers can generate a standard curve and read endogenous receptor levels directly without requiring additional reagent sourcing.

Typical applications include biomarker characterization during epithelial-mesenchymal transition studies, tumor microenvironment profiling, and cytokine pathway analysis, where receptor abundance is compared across treated and untreated experimental conditions, and where altered TGF-beta RII expression can be correlated with disease progression or pharmacological response in vitro.